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Chemical sciences literature

Application notes

Movie

  • StreamHR Rapide - nasal spray

    Using a Renishaw inVia confocal Raman microscope and WiRE™ software to image a drop of nasal medication. The image build up is shown at true data collection speed using StreamHR Rapide.

Application examples

We have also produced a range of application examples, including the following.

If you would like to find out more, please contact your local representative using the button below, quoting the relevant document reference.  

Document reference

 Description
AS008

Imaging detergent powder

Reveal information about powder mixtures with inVia and StreamLine imaging. In this example, single component domains and their distribution are quantified from a large powder area.

AS009

Imaging a pharmaceutical tablet

Reveal information about pharmaceutical formulations with inVia and StreamLine imaging. In this example, active pharmaceutical ingredient (API) domains and their distributions are quantified from an entire tablet section.

AS010

Imaging inhaler constituents

Reveal information about pharmaceutical formulations with inVia and StreamLine imaging. In this example, inhaler active pharmaceutical ingredients (API's) are identified and their relative locations compared.

 AS011

Imaging coated nasal spray particles

Reveal information about pharmaceutical formulations with inVia and StreamLine imaging. In this example, nasal spray particles are identified, with the active pharmaceutical ingredient (API) being shown to coat the excipient carrier paritcle.

 AS012

3D imaging a polymer laminate

Reveal information about multi-layered polymer films with inVia and 3D imaging.

 AS015

Imaging Pirinase nasal spray

Reveal information about pharmaceutical formulations with inVia and StreamLine imaging. In this example, API domains and their distribution are quantified from a Pirinase droplet.

 AS018

Analysing LA modes in polyethylene

Reveal low wavenumber Raman bands with inVia. Here, the longitudinal acoustic mode (LAM) of high density polyethylene is shown.
 AS019

Analysing lattice modes in sulfur

Reveal low wavenumber Raman bands with inVia. Here, the lattice modes (LAM) of sulfur are observed.

 AS020

Analysing rotational modes of gases

Reveal low wavenumber Raman bands with inVia. Here, the rotational modes of atmospheric air bands are observed.

 AS022

Analysing the composition of Piriton in high definition

This case study reveals the composition of an entire tablet in high definition with inVia.

 AS029

Low wavenumber Raman imaging

Low wavenumber Raman bands contain important chemical and structural information. Traditionally low wavenumber Raman bands are observed using spectrometers with triple diffraction gratings, which do not provide sufficient Raman throughput to make imaging feasible. Renishaw's range of Eclipse filters for inVia make imaging of low wavenumber Raman bands easy.

 AS032

Quantifying the composition of a SINGULAIR® tablet in high definition

Improve the accuracy of quantifying active pharmaceutical ingredient (API) domain sizes and amounts using inVia's high definition StreamLine™ imaging. SINGULAIR® (generically known as montelukast sodium) is a medication used to improve symptoms of asthma and allergic rhinitis. In this example, the SINGULAIR® API domains are quantified and compared. Different spatial resolution images show the benefit of generating large, high definition data.

AS054

Confocal Raman imaging of yogurt

Raman imaging of yoghurt can provide information on its protein-lipid network, the packing order of lipids and hydration, without employing any stains.