From drug discovery to formulation, development, and trouble shooting, our systems give you answers.
APIs, excipients and more
Renishaw's Raman systems have the performance and flexibility you need to analyse all your pharmaceutical materials.
- Identify and differentiate API polymorphs and excipients
- Generate images of the formulations used in tablets, inhalers and nasal sprays at sub-micrometre spatial resolution
- Use our dedicated high-throughput polymorph screening capabilities
- Study the thermal behaviour of drugs using advanced temperature control
- Fast, quantitative analyses of entire tablets and powder blends
- Determine the uniformity of mixing
- Analyse API and metabolites in cells and tissue
- Identify contaminants
One spectrum reveals all
Save time. Use SynchroScan to reveal all the key Raman bands; at high spectral resolution, over the entire Raman range, in just one data collection. See lattice modes, OH bands, and everything in-between. Spot the most subtle sample differences wherever they occur in the spectrum.
Generate images rapidly
Rapidly generate images of your formulations with StreamLine™. This uses line focus illumination, allowing you to use higher laser powers without risk of sample damage, thereby reducing experiment times.
Generate images of formulations
Ensure your chemical images are representative; use Renishaw's StreamLine. You can change resolution to suit your domain size and, because Renishaw's WiRE software can cope with massive data files, you can analyse over the entire sample surface. Powerful Renishaw features, such as Slalom (to ensure the whole surface is sampled) and HD imaging (to get crisp clear images), provide all the options you need, whatever your formulation.
21 CFR 11
Renishaw's WiRE software supports 21 CFR part 11 compliance.
Download an application note
Application note: Study the stability of pharmaceutical formulations with Raman microscopy
Many pharmaceutical materials are highly sensitive to changes in temperature and humidity which can affect their crystalline structure. Knowing the stability of these polymorphs and hydrates, in different conditions, is critical to ensure products are safe, efficient and can be patent protected.
Application note: Investigate pharmaceutical solid dose products using the inVia confocal Raman microscope
With so many components and properties, determining the composition, domain size and distribution of patent-expired commercially available formulations is highly desirable. This information creates opportunities to replicate an existing product without the need for lengthy development and prohibitive costs.
Application note: Transmission Raman for monitoring pharmaceuticals
Whether at the research and development stage, or manufacturing, the inVia Raman microscope offers simple and fast transmission Raman analysis. Benefit from the incredible chemical specificity and sensitivity of inVia using a transmission Raman configuration.
Watch a movie
StreamHR Rapide - nasal spray
Using a Renishaw inVia confocal Raman microscope and WiRE™ software to image a drop of nasal medication. The image build up is shown at true data collection speed using StreamHR Rapide.
Raman images revealing the chemical composition and distribution on the surface of an unprepared pharmaceutical tablet
StreamLine and LiveTrack focus-tracking were used to generate the tablet image, where the different components are colour coded.
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