The Renishaw RA816 Biological Analyser

The new RA816 Biological Analyser

The Renishaw RA816 Biological Analyser is a compact benchtop Raman imaging system, designed exclusively for biological and clinical research.

Imaging and molecular medical diagnostic techniques can be sensitive and specific to information related to the initiation and progression of disease and pathology. However, these techniques require contrast agents (stains and labels) or molecular tags, which can be costly in time (processing and review expertise) and money.

Use the RA816 Biological Analyser to identify and assess biochemical changes associated with disease formation and progression. There is little to no sample preparation, and no contrast agents or tags are needed.

The system provides a practical solution for analysing biological samples:

Easy to use hardware and software
No need for stains or labels
Minimal to no sample preparation
Obtain full range of biochemical information (no need for prior knowledge of specific molecular targets)

The system is designed specifically for biological and clinical sites:

Compact and transportable
Optimised microscopic technology:
- Autofocusing (LiveTrack™ focus-tracking technology)
- View samples at low and high magnification with minimum effort
Dedicated disease classification model building and testing
Dedicated tissue accessories and substrates
Designed for disease model transferability between instruments

Compliance

Class 1¹ laser product (Class 3B available on request)

¹As defined by IEC 60825-1:2014

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The Renishaw Biological Analyser RA816

The Renishaw Biological Analyser is a compact benchtop Raman imaging system that redefines tissue and biofluid analysis. It is easy to use, yet gives rich biochemical information about the biological samples being analysed.
[1920 x 1080] [286.2MB]

Image gallery

The Renishaw Biological Analyser

The Renishaw Biological Analyser - RA816
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Raman image of human osteosarcoma (bone cancer) cells.

Raman image of human osteosarcoma (bone cancer) cells, showing the nuclei (green), nucleoli (red), membrane bound organelles (cyan) and the cell body (yellow – thick region, blue – membranous area). Renishaw thanks Dr Frederick Coffman, Rutgers New Jersey Medical School, USA, for providing the cell sample.
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Imaging of human brain tissue

Imaging of human brain tissue. Comparison of (a) white light and (b) Raman-false-coloured composite score image of cerebellum whole follicle showing arbor vitae/white matter (red), granule cell layer (green), molecular layer (dark blue) and meninges (pia, arachnoid and dura mater) (cyan)
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Raman images of rat mandible

(a) 2D and (b) 3D Raman images showing variation in surface topography of a rat mandible, as determined using Renishaw LiveTrack technology.
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Biological Analyser accessories

Some of the accessories available for the Renishaw Biological Analyser
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The Renishaw Biological Analyser

The Renishaw Biological Analyser - RA816
[5616 x 3744] [8.9MB]

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Product note: The Renishaw Biological Analyser
The Renishaw Biological Analyser is a compact benchtop Raman imaging system that redefines tissue and biofluid analysis. It is easy to use, yet gives rich biochemical information about the biological samples being analysed.

Product note: The Renishaw Biological Analyser

The Renishaw Biological Analyser is a compact benchtop Raman imaging system that redefines tissue and biofluid analysis. It is easy to use, yet gives rich biochemical information about the biological samples being analysed.
[1.1MB]
Application note: Classification of brain glioma tumours using the Renishaw Biological Analyser
In a study conducted with the University of Oxford Neuropathology Department in the United Kingdom, we demonstrated discrimination between diseased and healthy brain tissue using the Renishaw Biological Analyser - RA816.

Application note: Classification of brain glioma tumours using the Renishaw Biological Analyser

In a study conducted with the University of Oxford Neuropathology Department in the United Kingdom, we demonstrated discrimination between diseased and healthy brain tissue using the Renishaw Biological Analyser - RA816.
[384kB]
Application note: Monitoring of transdermal drug delivery in skin using the Renishaw Biological Analyser
Detecting the presence and depth of penetration of drug compounds in skin can prove challenging, current technologies fail to achieve adequate penetration through layers of dermal tissue. In this study, Raman spectroscopy using the Renishaw Biological Analyser - RA816 confirmed the presence of a topical compound in the epidermis and reticular dermis with high specificity and sensitivity.

Application note: Monitoring of transdermal drug delivery in skin using the Renishaw Biological Analyser

Detecting the presence and depth of penetration of drug compounds in skin can prove challenging, current technologies fail to achieve adequate penetration through layers of dermal tissue. In this study, Raman spectroscopy using the Renishaw Biological Analyser - RA816 confirmed the presence of a topical compound in the epidermis and reticular dermis with high specificity and sensitivity.
[705kB]

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Latest Biological Analyser news

Scientists from The University of Manchester team up with Renishaw to analyse tissue

Renishaw has collaborated with scientists at The University of Manchester to show the ability of Raman spectroscopy to analyse skin tissue.

Ground breaking Raman work presented at conference

Presenting ground breaking Raman work at the Cancer Research UK Brain Tumour Conference Renishaw has collaborated with scientists at Oxford Radcliffe Hospital to investigate the capability of Raman spectroscopy to classify gliomas, in terms of their genetic subtypes, using different pathological preparations.